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Valrubicin is actually a semisynthetic analog on the anthracycline doxorubicin, which can have an effect on various interrelated biological functions, the vast majority of which are associated with nucleic acid metabolism. The drug is administered straight into your bladder for that cure of bladder most cancers.
Daunorubicin interacts with DNA by intercalation and inhibition of macromolecular biosynthesis. This inhibits the development of the enzyme topoisomerase II, which relaxes supercoils in DNA for transcription.
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Epirubicin is favoured in excess of doxorubicin, the most popular anthracycline, in certain chemotherapy regimens because it appears to lead to much less side effects. In 1999 epirubicin gained FDA acceptance being a component of adjuvant therapy in node-beneficial individuals.